Dr. Rodolfo Acuna-Soto is a Professor at the Department of Microbiology and Parasitology at the Medical School and College of Geography of the Faculty of Philosophy and Letters, both at the National Autonomous University of Mexico. He received an M.D. degree from the National Autonomous University of Mexico followed by a medical residence in pathology at the National Institutes of Pediatrics, Cardiology and Nutrition in Mexico City. He holds M.Sc. and a D.Sc. in Tropical Public Health from Harvard University, (Thesis director: Dr. Dyann F. Wirth) and a postdoctoral fellowship at the division of Infectious Diseases, Beth Israel Hospital, Boston (Principal investigator: Dr. Peter Weller). Since his return to Mexico, Dr. Acuna has worked on a long-term project that attempts to understand and quantify the role and interaction of environmental and biological variables associated with the emergence, circulation, control, emergence and re-emergence of infectious diseases. The basis of this approach is the use of reconstructions of endemicity patterns and small and large epidemic events over long periods of time. All the historical information is obtained from original sources in documentary and digital archives from the fifteenth century to the present. The analysis is fundamentally collaborative and multidisciplinary, of particular importance are the participation of experts in Climatology, Epidemiology, Archeology, Anthropology, Geography, Demography, Mathematical Modeling and Infectious Diseases.